Category Archives: News

Wednesday, October 27 |Arthritis Foundation

October 2021 Arthritis News Roundup

The Arthritis Foundation is your trusted source for arthritis-related news and COVID updates that affect people with arthritis. Here’s a wrap-up of the headlines from this past month.

The latest in COVID-19 News & Arthritis

FDA Committee Greenlights COVID Vaccines for Young Kids

The Vaccine and Related Biological Products Advisory Committee for the U.S. Food and Drug Administration (FDA) voted by a majority to authorize the emergency use of Pfizer-BioNTech’s COVID vaccine for children ages 5 through 11.Read the latest.

FDA Authorizes Boosters for Moderna and J & J, Allows Mixing

The U.S. Food and Drug Administration (FDA) has authorized booster doses for the Moderna and Johnson & Johnson COVID-19 vaccines, while also allowing boosters to be given interchangeably with any of the other vaccines in people who are eligible to get them.Learn more.

CDC Research Shows Children Equally Vulnerable as Adults to COVID

According to new research from the Centers for Disease Control and Prevention (CDC), children had similar infection rates, compared with adults, confirming there is risk of people of all ages. The research revealed that schools without mask requirements were three-and-a-half times more likely to have COVID-19 outbreaks than those enforcing mask mandates.Read more about it.

Get the latest on managing your arthritis during the COVID pandemic in theCare & Connect资源中心。

In Other Arthritis News

Prevalence of Arthritis in the U.S. Continues to Rise

National prevalence of arthritis and arthritis-attributable activity limitations continue to increase. According to the CDC, 58.5 million (23.7%) U.S. adults now have arthritis — 25.7% of whom have arthritis-attributable activity limitations. Read more aboutthe impact of arthritis．

New Finding: 71% of Active Adults With Arthritis Walk for Physical Activity

Physical activity can reduce pain, disability and functional limitations while also improving mental health and quality of life in adults with arthritis. Just over one-third of adults with arthritis are aerobically active. New research from the CDC shows approximately 71% of adults with arthritis who were physically active in the past month reported walking as one of their two most frequent activities.Learn how other activities ranked.

And be sure to check outWalk With Ease, the Arthritis Foundation’s walking program proven to reduce arthritis symptoms and improve health.

FDA Approves Combo Pill for Severe, Acute Pain

美国食品和药物管理局(FDA)批准了一种含有塞来昔布和曲马多的复方药物，用于治疗急性疼痛严重到需要阿片类镇痛药，而替代疗法不能提供足够的疼痛缓解。在这里获取详细信息。

To learn more ways to take control of pain, visitarthritis.org/pain．

FDA Approves First Nasal Spray to Treat Dry Eye

TheFDA has approved varenicline solution(Tyrvaya), the first nasal spray given the greenlight to treat dry eye disease. Varenicline solution will provide an alternative to the immunomodulators currently available.

Learn about theconnection between dry eyes and arthritis．

Updates to Guidance for Shingles and Pneumococcal Vaccines

The CDC Advisory Committee of Immunization Practices (ACIP) voted torecommend zoster vaccine recombinant, adjuvanted (Shingrix) for the prevention of shingles in immunodeficient or immunosuppressed adults age 19 or older. During the same meeting, ACIP also voted to recommend pneumococcal vaccines for routine use in adults older than 65 and in adults ages 19 to 64 with chronic conditions such as diabetes, chronic heart disease, chronic liver disease and HIV, and disease risk factors like smoking and alcoholism.

National Emergency Declared for Mental Health in Children

The American Academy of Pediatrics (AAP), the American Academy of Child and Adolescent Psychiatry (AACAP) and Children’s Hospital Association havedeclared a national emergency in children’s mental health．根据这两个组织的说法，新冠肺炎疫情在本已严峻的挑战基础上造成了严重损失，迫切需要改变政策。

Know the signs andhow to recognize emotional distress in your child with juvenile arthritis．

High-Intensity Resistance Training Bests Pilates for Better Bone Density in the Spine

An eight-month high-intensity resistance and impact training program (HiRIT, Onero) led to greater gains in lumbar spine bone mineral density (BMD) and leg/back strength than a low-intensity Pilates-based program.Learn more.

Retraining the Brain May Help Relieve Chronic Back Pain

根据一项新的研究，病人对疼痛的感知在疼痛的结果中起着关键作用。心理疗法改变了个体对疼痛的信念，不仅提供了持久的慢性疼痛缓解，而且还改变了与产生疼痛有关的大脑区域。Read more about it.

Exercise Appears to Improve Bone Structure, Not Density

最近的一项研究得出结论，骨骼健康不仅仅是严格意义上的骨密度，绝经后骨量较低的女性应该获得足够的钙和维生素D，并参加负重锻炼。Learn more.

Thursday, September 30 |Arthritis Foundation

September 2021 Arthritis News Roundup

The Arthritis Foundation is your trusted source for arthritis-related news and COVID updates that affect people with arthritis. Here’s a wrap-up of the headlines from this past month.

The Latest in COVID-19 News and Arthritis

WHO Monitors New ‘Mu’ COVID-19 Variant

The World Health Organization is monitoring a new coronavirus variant called “mu,” which the agency says has mutations that have the potential to evade immunity provided by a previous COVID-19 infection or vaccination.Get details here.

NIH to Study COVID Vaccine Booster in Autoimmune Patients

The National Institute of Allergy and Infectious Diseases has begun a phase 2 trial toassess the antibody response to a booster dose辉瑞- biontech、Moderna或杨森的疫苗对自身免疫性疾病患者没有反应，他们最初的COVID-19疫苗方案。

COVID-19 Vaccine Elicits Antibodies in 90% Taking Immunosuppressants

Nearly 90% of people taking immunosuppressants to treat autoimmune conditions produce an antibody response to COVID-19 vaccination, but the response is weaker than those generated by healthy people, according to a new study.Learn more.

Get the latest onArthritis and COVID-19 vaccines FAQsin ourCare and Connectresource hub.

Nasal Cartilage Relieves Knee Osteoarthritis

Cartilage cells from the nasal septum cannot only help repair cartilage injuries in the knee — they can also withstand the chronic inflammatory tissue environment in osteoarthritis (OA) and even counteract the inflammation, according to researchers at the University of Basel and the University Hospital of Basel.Read all about it.

Drug Adherence Tied to Genetic Influences, Not Side Effects

The results of new research suggest that drug adherence pertains more to an individual’s genetic predisposition to particular behaviors than to underlying biological factors, such as the adverse effects of a specific drug, the researchers conclude.Learn more.

Cannabis Use Tied to Poorer Outcomes of Total Hip, Knee Replacement

Cannabis use before total knee or hip replacement is associated with increased medical and implant-related complications, according to new research presented at the annual meeting of the American Academy of Orthopaedic Surgeons.阅读更多。

TheArthritis Foundation developed guidance for adults with arthritiswho are exploring CBD use as a treatment for managing pain and other symptoms of arthritis. Learn more aboutwhat you should know about CBDbefore trying it.

And learn more abouttotal kneeandhip arthroplasty．If you’re exploring whether surgery is right for you, listen to the podcast episode onArthritis Pain & Surgery．

In Other Arthritis News

Arthritis@Work for Corporate Wellness Programs

The Arthritis Foundation is offering employers free turnkey tools and resources to support their employees with arthritis. As the second largest driver of employee health care costs, arthritis is responsible for 172 million lost workdays each year. Integrated into existing corporate wellness programs,Arthritis@Work是一个双赢的方式，为雇主保护他们的底线，照顾那些关心他们的业务。

Novartis Gets FDA Fast-Track Designation for LNA043 in Knee OA

The Swiss drug maker said it isdeveloping LNA043 as a potential first-in-class disease-modifying treatment for OA．FDA的快速通道项目旨在促进严重或潜在威胁生命的疾病的治疗方法的发展和加快审查，而这些疾病的医疗需求没有得到满足。

No Sex Difference Seen for Ankylosing Spondylitis

在一项针对军事人员的大型研究中，强直性脊柱炎(AS)的发病率在男性和女性之间没有差异，这对之前关于该疾病以男性为主的假设提出了质疑。Read about the study.

Osteoarthritis: New Genetic Risk Factors and Novel Drug Targets

Researchers have found new genetic risk factors for OA and identified novel drug targets. Their finding is a milestone toward the development of the first ever curative treatment for OA.Learn more.

TPX-100 Delays Bone Shape Change, Stabilizes Cartilage in Bilateral Knee OA

TPX-100, a promotor of osteoblast and chondroblast differentiation, is a potential therapy for OA. A new retrospective study compared MRI 3D femoral bone shape changes (B-scores) after intra-articular TPX-100 or placebo and analyzed therelationship between cartilage thickness and bone shape changeover 12 months.

For pain management resources and tools, visitarthritis.org/pain．

Tuesday, September 21 |Arthritis Foundation

Yoga: So Much More Than Just Movement

By Rebecca Gillett, MS OTR/L, Live Yes! With Arthritis Podcast Co-host

September is Pain Awareness Month, and in this podcast episode,Mindful Movement Part 2: Yoga,we’re exploring ways to keep our bodies moving to prevent arthritis pain from limiting our lives. In the last episode, we focused on mindful movement and tai chi. This time, we’re diving into mindful movement of yoga and arthritis.

When you have arthritis, you probably think, “No way can I do those poses with my joint pain. Yoga is going to make my pain worse!” That’s exactly how I felt when I was first diagnosed.

I have a favorite cartoon that demonstrates what I think about arthritis and yoga. Google it for a good laugh. It shows the Tin Man fromThe Wizard of Ozin a yoga class. I’ll wait…. You’re welcome.

我20岁出头就开始上瑜伽课，而且非常喜欢。虽然那是很久以前的事了，但我仍然记得下课时那种平静和正能量的感觉。事实上，我清楚地记得有一节课结束时，我是如何放松到睡着的!我醒来时看到灯亮了，大家都走了。想象一下:瑜伽练习让你处于一种平静、放松的状态，你会睡着。

但在我26岁的时候，我被诊断出患有类风湿性关节炎，在最初的两年里，我一直在与疼痛作斗争，以至于我停止了瑜伽。因为手腕疼痛，我觉得我再也做不下去了。

I often talk about how we can sometimes get “stuck” in our pain: We cannot see past the pain to solutions that may be right in front of us because we are in survival mode. We struggle to do some of the most basic things — getting out of bed, brushing our teeth, going down the stairs. Any type of movement can be daunting, so the idea of doing a warrior or mountain pose sounds even less achievable.

This episode,Mindful Movement, Part 2: Yoga,was a fantastic reminder to me about what the practice of yoga truly entails and how you can adapt yoga to suit your needs. Our guest expert, Steffany Moonaz, PhD, founded the Yoga for Arthritis program after eight years at Johns Hopkins University, where she studied the effects of yoga for people living with arthritis. She helped us remember that there’s a way to practice yoga for everyone, no matter where you are in your journey with arthritis. Whether you practice chair yoga or modify a few poses, alone at home or in a group class, the physical and mental health benefits can go a long way to improving your overall well-being. Dr. Moonaz also shared ways to make sure you can find a yoga practice that works for you and a yoga instructor that’s right for your needs.

Tune in to this episode to learn how you can start incorporating yoga practice into your daily routine today.现在听!

We Bid Thee Farewell, Julie!

Be sure to listen through to the end of this episode, as we chat with co-host Julie Eller. This is the final episode we recorded together before she left to start a master’s program in public health. Julie has been a force to be reckoned with while on staff at the Arthritis Foundation. She helped grow our grassroots advocacy efforts and she worked tirelessly to ensure the patients’ perspective is infused in everything we do that’s health care-related. I can’t imagine anyone better to co-host this podcast with, and in the process, how much we’d get out of doing this together. I’m grateful for every dance, every smile, every blooper and all of the laughter (and sometimes tears) we shared throughout this journey together. Most of all, I am forever grateful for the lifelong friendship we share. Best wishes, my pod sister, Julie!“哦，你要去的地方!”

Friday, September 3 |Arthritis Foundation

FDA Strengthens Warnings for Xeljanz, Olumiant and Rinvoq

By Jill Tyrer | Sept. 3, 2021

The Food and Drug Administration has issued warnings about the use oftofacitinib (XeljanzandXeljanz XR)as well asbaricitinib (Olumiant)andupadacitinib (Rinvoq)．这三种药物都属于Janus激酶(JAK)抑制剂类，用于治疗关节炎和其他炎症条件。

一项大型随机安全临床试验将托法替尼与另一种称为肿瘤坏死因子(TNF)抑制剂的药物用于类风湿关节炎(RA)进行了比较。根据FDA的公告，结果显示托法替尼比抗肿瘤药物有更高的心脏相关问题的风险，包括心脏病发作、中风、癌症、血栓和死亡。As a result, theFDA will require a “boxed warning”on the package, its most serious warning.

但如果你服用了其中一种药物，不要停，医生说。目前还没有足够的数据来准确理解如何解读该公告，以及谁可能受到影响。

“There’s nothing in this that says there’s an urgent need to stop the drug, and people should absolutely not stop on their own without discussing with their rheumatologist,” says Eric Ruderman, MD, rheumatologist and professor of medicine at Northwestern University Feinberg School of Medicine.

Tofacitinib is approved to treat polyarticular juvenile idiopathic arthritis, psoriatic arthritis and rheumatoid arthritis, as well as ulcerative colitis. It is used off-label in certain cases for psoriasis and for hospitalized COVID-19 patients. Baricitinib and upadacitinib are each approved to treat RA.

Safety Trial

When it approved tofacitinib, the FDA required drugmaker Pfizer to conduct the safety trial in RA patients who were takingmethotrexateto find out its risks for heart issues, cancer and infections. Trial participants were over 50 years old with at least one risk factor for heart disease. Researchers looked at two doses of tofacitinib — 5 mg twice a day, which is approved for RA treatment, and 10 mg twice a day.

FDA今年早些时候警告说，只有使用更高剂量的托法替尼才会增加血栓和死亡的风险。但随着试验的结束，结果显示，剂量越低，风险也越高。FDA现在将限制这些JAK抑制剂的使用，仅用于对TNF抑制剂没有充分反应的患者。

该试验被设计为“非劣效性研究”，试图表明使用托法替尼的风险并不高于使用TNF抑制剂。Ruderman博士说:“基本上，Xeljanz并没有达到这种非劣效性，所以他们不能肯定地说，在某些安全事件中，Xeljanz并不比TNF[抑制剂]更差。”

Questions Remain

Rheumatologist Jasvinder Singh, MD, MPH, professor of Medicine and Epidemiology at University of Alabama, Birmingham, and director of rheumatology research at Birmingham VA Medical Center, is waiting for more information before drawing any conclusions about who should be concerned and to what extent. The study itself was not yet available.

“我是一名流行病学家，所以我喜欢看这些数字。这通常有助于我理解什么是真正的风险。这就是为什么我对做出任何决定性结论有点怀疑的原因。”例如，一名患有高血压的52岁女性和一名吸烟的62岁男性，都有高胆固醇和糖尿病，这两种情况都符合这项研究的研究对象。“但这是两种截然不同的情况，”他解释道。“所以，当我们说到心血管风险因素时，哪些因素，多少因素，在年龄和性别上有什么不同?”

Plus, Dr. Ruderman adds, “having RA itself is a risk factor for cardiovascular events and blood clots and cancers. Is everybody high risk? We don’t know.”

Drs. Singh and Ruderman also want to learn more about the warnings for baricitinib and upadacitinib. Safety trials have not directly compared either of those to anti-TNFs, but because they work in the same way in the body that tofacitinib does, the FDA expects the same outcomes and extended the warnings to them.

“What [the FDA] said is they don’t have any data forRinvoqorOlumiant,but since they’re kind of the same class with a similar mechanism, they don’t know that those don’t have the same issues, so they’re going to include the same kind of language in those labels as well,” Dr. Ruderman says.

Drug Options

Tofacitinib, approved in 2012, was the first JAK inhibitor approved to treat arthritis. Baracitinib followed in 2018, and upadacitinib the following year. They are seen as an alternative to biologics and are preferred by many patients because they are in pill form rather than injection or infusion.

Still, JAK inhibitors are not as widely prescribed for arthritis as other medications, including biologics, which have been around longer and have a more robust track record. Dr. Singh estimates about 10% of eligible patients use JAK inhibitors.

Several options are available if you and your doctor decide it’s a good idea to switch. But Drs. Ruderman and Singh are unlikely to advise their patients to make any changes until they have more information, they say.

拉德曼博士说:“在我看到FDA的最终建议和它们所依据的研究数据之前，我真的不知道该告诉他们什么，所以在我获得更多信息之前，我不会改变任何人的药物。”

What Should You Do?

If you take one of these medications, don’t stop taking it, but be aware of the warning, and reach out to your rheumatologistforguidance.

FDA在声明中说:“即使按照规定正确使用，所有药物都有副作用，但总的来说，服药的好处大于这些风险。”“然而，如果你现在或过去吸烟，或曾经有过心脏病发作、其他心脏问题、中风或血栓，你应该告诉你的卫生保健专业人员，因为这些药物可能会使你面临更高的严重问题的风险。”

The FDA recommends that you seek emergency care if you experience any of the following, which could be a sign of a heart attack, stroke or blood clot:

    • Discomfort in the center of your chest that lasts for more than a few minutes, or that goes away and comes back
    • 胸部、喉咙、颈部或下巴严重发紧、疼痛、压迫或沉重
    • Pain or discomfort in your arms, back, neck, jaw or stomach
    • Shortness of breath with or without chest discomfort
    • Breaking out in a cold sweat
    • Nausea or vomiting
    • Feeling lightheaded
    • Weakness in one part or on one side of your body
    • Slurred speech
    • Drooping on one side of your mouth
    • Swelling of a leg or arm
    • Leg pain or tenderness, or red or discolored skin in the painful or swollen leg or arm

And tell your doctor if you experience any of these symptoms:

    • Swelling of lymph nodes in your neck, armpits or groin
    • Constantly feeling tired
    • Fever
    • Night sweats
    • Persistent or worsening cough
    • Difficulty breathing
    • Hoarseness or wheezing
    • Unexplained weight loss

Updated Sept. 5 with comments from Drs. Singh and Ruderman

Tuesday, July 27 |Arthritis Foundation

July 2021 Arthritis News Roundup

The Arthritis Foundation is your trusted source for arthritis-related news and COVID updates that affect people with arthritis. Here’s a wrap-up of the headlines from this past month.

The Latest in COVID-19 News & Arthritis

Delta Variant Causing States & Counties to Consider Mask Mandates
The highly contagious Delta variant of COVID-19 is causing concern across the U.S. as some states are seeing an increase in cases and hospitalizations. Some areas areconsidering mask mandatesagain, especially indoors.

Stay up to date with your local health department guidelines and check the Arthritis Foundation’s website regularly forCOVID-19 & Arthritis FAQs．

Fauci: Immune Compromised May Need COVID-19 Vaccine Booster
Dr. Anthony Fauci, director of the U.S. National Institute of Allergy and Infectious Diseases and the chief medical advisor to the president, says people who are immune compromised may need a COVID-19 booster vaccine. He stated that patients with transplants, undergoing cancer chemotherapy and people with autoimmune diseases who are on immunosuppressant treatments may all need a vaccine booster to increase antibodies to the virus, especially as the Delta variant continues to spread. He also said revised mask guidance by top health officials is under active consideration.Get the details．

Autoimmune Rheumatic Disease Does Not Influence Immune Response Against COVID-19
Despite suspicions that patients with autoimmune rheumatic diseases (AIRD) may have worse immune responses against COVID-19, research indicates that this patient population did not differ from the general population in protective antibody responses, according to astudy published in Springer．

Vaccine Hesitancy for Some With Rheumatic Diseases Weighs Heavy

Despite guidance from the American College of Rheumatology, some patients with rheumatic diseases are still very concerned about getting the COVID-19 vaccine. Dr. Jeffrey Curtis, MD, MPH, a University of Alabama at Birmingham rheumatologist who leads the American College of Rheumatology COVID-19 vaccine task force, says the concerns are valid. However, the benefits to vaccination outweigh the risk of having severe COVID or the potential for disease flare.Read more．

For details on COVID-19 vaccine recommendations for people with arthritis, visit the Arthritis FoundationCare & Connecthub.

Study Suggests Lasting Immunity After COVID-19, With a Big Boost from Vaccination
After an infection with SARS-CoV-2, most people — even those with mild infections — appear to have some protection against the virus for at least a year, a recent follow-up study of recovered patients published inNaturesuggests. What’s more, this and other research demonstrates that vaccinating these individuals substantially enhances their immune response and confers strong resistance against variants of concern, including the B.1.617.2 (Delta) variant.Read the study．

In Other Arthritis News

FDA & Arthritis Foundation Make OA Priority Discussion

The Arthritis Foundation partnered with the U.S. Food and Drug Administration (FDA) to host a workshop recently on developing new treatments with long-term benefits for OA.Learn moreabout what’s being done to tackle treatments for OA.

Taking a Step Toward Discovering the Cause of Joint Disease
一项新的研究发现，GDF5基因附近的开关与膝骨关节炎和髋关节发育不良有关。这项新信息可以为定向筛查和治疗奠定基础。Read more．

AbbVie, Lilly Face Fresh Delays in FDA Approval for Expanded Use of Arthritis Drugs

JAK (janus kinases) inhibitors have come under the U.S. Food and Drug Administration’s scrutiny, after preliminary results from a safety trial of Pfizer’s JAK inhibitor drug earlier this year showed an increased risk of serious heart problems and cancer in patients.Learn more．

Association Between Psoriasis and RA
越来越多的证据表明银屑病和风湿性关节炎风险增加之间的联系，这强调了需要进行前瞻性研究，以加强我们对两种疾病患者的病程和最佳治疗的理解。Read more．

Biologic Treatments Could Mitigate Psoriatic Arthritis Risk
A new study finds that treatment with biological disease-modifying antirheumatic drugs (DMARDS) for people with psoriasis may lower the incidence of developing psoriatic arthritis later.Learn more．

Low-Dose Steroid Use in RA May Still Cause Risk for Vertebral Fractures

A new study reports that patients with rheumatoid arthritis (RA) being treated with low-dose glucocorticoids are still at risk for increased vertebral fractures.Read the report．

Learn more about corticosteroids和关节炎。

3D-printed Knee Implants Could Cut Surgery Times and Improve Arthritis Treatment
Known as Tailored Osteotomy for Knee Alignment (TOKA), this treatment improves the operative procedure and fit of high-tibial osteotomy (HTO) plates used to realign a patient’s knee, making them more stable, comfortable and better able to bear weight than existing generic plates.Learn more about the technique以及它如何简化HTO手术，使手术更快，因此更安全。

Monday, July 26 |Arthritis Foundation

What chronic pain takes away, Vim gives back!

To kick off Arthritis Awareness Month in May, the Arthritis Foundation launched our newVim app— a unique, personalized tool to help people with arthritis easily find resources they need to manage their pain. The app also helps keep track of conditions and treatments, set and achieve goals, and connect with others for tips and encouragement.

The app stems from input received from 40,000 survey respondents in the Foundation’s ongoing生活是的!INSIGHTS study, which is summarized in ourHow It Hurts report．在开发Vim的过程中，我们从关节炎患者、医疗保健专业人员和其他疼痛管理专家那里寻求广泛的反馈。

该应用程序可以帮助用户根据自己的情况和需求设定SMART目标;目标是具体的，可衡量的，可实现的，相关的和有时限的。用户还可以通过一个由七个类别的专家内容组成的深度库获得关于如何最好地管理慢性疼痛的信息和想法。也许最重要的是，Vim培养了一种具有共同经历的社区精神，让人们聚集在一起，倾听和激励彼此，帮助更容易地管理疼痛。

迅速崛起的纳斯卡赛车手娜塔莉·德克尔是一名关节炎基金会冠军大使，她从小患有关节炎，并继续与它的挑战作斗争。她说，Vim帮助她养成了冥想的习惯，让她的思想放松，并设定了像定期拉伸运动这样的身体目标。她说:“我喜欢你能为别人加油。这很酷。”

Vim is made possible by Arthritis Foundation sponsors who believe it’s a great solution to help people with arthritis find their Yes.

A representative of Vim Inaugural Sponsor TYLENOL says:

“TYLENOL®是关节炎基金会的骄傲的合作伙伴，也是基金会三年计划征服疼痛的首次赞助者。我们选择支持Vim和疼痛倡议，因为我们相信鼓励和教育的力量，是帮助那些遭受关节炎疼痛的人过上更充实生活的关键工具。”

A spokesperson for Flexion Therapeutics, another Vim Inaugural Sponsor, adds:

作为一家致力于改善面临痛苦的骨关节炎患者生活的公司，Flexion Therapeutics荣幸地支持关节炎基金会的Vim应用程序，这是一个强大的工具，旨在帮助关节炎患者，包括骨关节炎，采取小的和大的步骤，管理慢性关节疼痛，削弱了很多人的这种疾病。”

Joe Tolman, founder of HurtSkurt, Vim Participating Sponsor, says:

“Becoming a Partner with the Arthritis Foundation and being part of the launch of the pain initiative and Vim app was an absolute no-brainer for us. The goal of HurtSkurt®是帮助人们以最有效的方式缓解疼痛，而Vim应用程序的目标是帮助患有关节炎的人管理他们的日常疼痛。如果我们的产品能让一个人每天都过得更好，那我们就是在做一件特别的事。能成为这个项目的一部分，我们感到非常兴奋。”

今天就从Vim开始吧。And see for yourself how much it can help give you back what chronic pain takes away.

Monday, June 28 |Arthritis Foundation

June 2021 Arthritis News Roundup

June has been a busy month for arthritis-related news. Here’s a wrap-up of the headlines from this past month.

Arthritis Foundation Releases Statement as Supreme Court Upholds Affordable Care Act
Earlier this month, the Supreme Court threw out a lawsuit that challenged the Affordable Care Act. The Arthritis Foundation issued a statement along with a letter of support from 33 other patient advocacy organizations.Read the statement．

Methotrexate Impairs COVID Vaccine Response
研究人员报告称，三分之一接受甲氨蝶呤治疗的免疫介导性炎症疾病患者对COVID-19疫苗的反应减弱。Learn more．

The Complex Situation for the Immunocompromised and COVID-19 Vaccines
Studies suggest the available shots don’t provide enough protection, leaving more than 9 million Americans with compromised immune systems stuck in a waiting game.Find out more．

Testing Third Doses of COVID Vaccine in Immunocompromised Patients
New study offers hope for protecting this vulnerable population from COVID-19.Learn more about this study．

Get expert guidance on vaccine efficacy for people with compromised immune systems or on certain arthritis medications.Read more．

Diet May Impact COVID-19 Severity
Plant-based and/or fish diets may help lessen the severity of COVID-19 infection, according to a study published online June 7 inBMJ Nutrition Prevention & Health．Find out more about the study．

Following an anti-inflammatory diet, like the Mediterranean diet, may help reduce body-wide inflammation.Find out more．

New ACR Guidelines for Rheumatoid Arthritis Treatments Finalized
美国风湿病学会发布了其2020年类风湿性关节炎治疗新指南，这是自2015年以来的首次更新。Read the new guidelines．

Get an expert breakdown of what the new ACR guidelines mean for patients with RA.Learn more．

Sleep Deprivation Linked With Cardiovascular Risk in Early Rheumatoid Arthritis
Patients with early rheumatoid arthritis have short sleep duration at night that is associated with cardiovascular disease risk factors, according to study findings published inACR Open Rheumatology．Learn more．

Osteoarthritis Associated With Elevated Risk of Parkinson Disease
研究人员假设，患有骨性关节炎的人可能有更高的风险发展为帕金森病。这是基于文献报道的OA相关的外周炎症可能导致大脑神经炎症，导致帕金森相关的神经退行性变。Read more．

Combination Immunomodulatory Therapies for Patients With Psoriatic Arthritis?
An article inArthritis & Rheumatologyfrom psoriatic arthritis erudites, Drs. Scher, Ogdie, Merola and Ritchlin, is bringing attention to the discussion about combination therapy in the complex field of seronegative spondyloarthropathies — specifically psoriatic arthritis.Read more．

Wednesday, May 26 |Arthritis Foundation

May 2021 Arthritis News Roundup

May has been a busy month for arthritis-related news and COVID updates that affect people with arthritis. Here’s a wrap-up of the headlines from this past month.

Taking Action For Better Access

生物药物和疗法可以减缓关节炎的进展，并让患者提高生活质量，但是，当保险计划剥夺了医生开最合适的治疗处方的能力，而没有首先强迫患者尝试保险公司所喜欢的治疗——这个过程被称为“步骤疗法”时，这些疗法往往变得无用。

In a new op-ed forThe Hill, American College of Rheumatology President Dr. David Karp and Arthritis Foundation President & CEO Ann Palmer are urging Congress to address this issue by passing theSafe Step Act．

You cantake action nowby contactingyour member of congressand asking them to support the Safe Step Act.

Millions of Immunocompromised Americans May Not Be Fully Protected by Coronavirus Vaccines

Early research shows that 15-80% of people with certain medical conditions are generating few antibodies after receiving coronavirus vaccines.阅读更多。

Learn what precautions people with certain forms or arthritis or on certain medications should take once vaccinated.View the slideshow．

NIH to Study How COVID-19 Vaccines Work in People With Suppressed Immune Systems

After research suggested they develop fewer antibodies from coronavirus vaccines, the National Institutes of Health has launched a study to understand how people with immune disorders respond to COVID-19 vaccines.Find out more about the study．

ACR Updates COVID-19 Vaccine Guidance for Managing Patients With Rheumatic and Musculoskeletal Diseases

Recently, guidance was updated to include new recommendations regarding mycophenolate, methotrexate, acetaminophen and nonsteroidal anti-inflammatory drug timing considerations for patients with rheumatic diseases.Learn more.

FDA, CDC Lift Suspension of Johnson & Johnson COVID Vaccine

The Centers for Disease Control and Prevention and the Food and Drug Administration lifted a 10-day pause on the Johnson & Johnson vaccine, but will issue a fact sheet to medical providers warning them of the potential for extremely rare but serious blood clots.Read more．

Majority of Parents Will Wait on Kids’ COVID Vaccine

根据对1258名父母的一项新调查，当FDA批准年幼的孩子接种COVID-19疫苗时，四分之三的父母不打算给他们的孩子接种。许多人说他们会等几个月，但整整三分之一的人说他们根本不打算给孩子接种疫苗。Find out more．

Got vaccine questions? Infectious disease and vaccine expert, Robert L. Murphy, MD, breaks down the severe risks of COVID-19 vaccines for people with arthritis and explains how to evaluate the true risk for yourself.Watch the Q&A．

Patients With Rheumatic Diseases Are More Likely to Avoid Health Care During COVID-19 Pandemic

Patients with certain forms of arthritis were more likely to avoid office visits and laboratory testing and discontinue DMARDs without physician indication during the early months of the COVID-19 pandemic, according to a study published inThe Journal of Rheumatology．Learn more．

Biologic Treatment Spacing Feasible for Some Rheumatic Disease Patients

BIOPURE研究结果显示，疾病缓解稳定或疾病活动度低的风湿病患者可以通过间隔剂量减少其生物(b)DMARD治疗，而不会发生疾病发作。Find out more．

Time Trends in Opioid Use Disorder Hospitalizations

A new study evaluates opioid use disorder–related hospitalizations and associated health care utilization outcomes in people with five common musculoskeletal diseases.Read the study’s findings．

Time to Screen for Older Patients’ Cannabis Use?

美国全国药物使用与健康调查(NSDUH)的一项分析发现，在过去十年中，50岁及以上的美国人使用大麻的人数增加了一倍多，近十分之一的人报告称在过去一年中使用了大麻。阅读更多。Read more．

Medical cannabis for arthritis pain relief is growing in popularity. Learn how to speak with your doctor about the benefits of medical marijuana.Get expert tips for speaking with your health care provider．

Telemedicine Is a Tool — Not a Replacement for a Doctor’s Touch

The pandemic has demonstrated that virtual medicine is great for many simple visits. But many of the new types of telemedicine being promoted by start-ups more clearly benefit providers’ and investors’ pockets, rather than yielding more convenient, high-quality and cost-effective medicine for patients.Find out more．

Clinicians ‘Should Be Cognizant of’ Racial, Cultural Disparities During RA Management

Clinicians should be aware of racial and cultural differences in the perception of health care and tailor their approach accordingly, and reduce potential health care disparities, noted a speaker at the 2021 Interdisciplinary Autoimmune Summit.Learn more．

Boosting the Presence of Darker Skin in Rheumatology Education

Studies are flagging racial and ethnic disparities in rheumatology training materials, pointing to a need to boost representation of darker skin tones and better educate physicians in evaluating this cohort. Not enough is known about these disparities in rheumatology education, despite the fact that minorities make up 40% of the population in the United States.Read more．

Arthritis uniquely affects marginalized segments of society. Their experiences are detailed in How It Hurts — the latest findings from the nearly 40,000 responses to the INSIGHTS survey.Read How It Hurts．

3D Biomaterial Used as ‘Sponge’ for Stem Cell Therapy to Reverse Arthritis

A new study of a 3D biomaterial scaffold design is showing promise, relieving pain and reversing arthritis in mice knee joints. The design slowly releases stem cells to ensure that implanted stem cells stick around.Read more about this study．

Improved Understanding of Damaging Immune Response in Rheumatoid Arthritis

Researchers within the Biomedicine Discovery Institute at Monash University have made a breakthrough in understanding the role played by high-risk immune genes associated with the development of rheumatoid arthritis (RA). Study results suggest that there may be an immune signature of RA development, providing a potential avenue for diagnostic development or a window of opportunity for therapeutic development.Learn more．

Shared Decision Making, Clinical Judgment Take Priority Where OA Guidelines Diverge

美国风湿病学会最先进临床研讨会的一位发言者指出，共同决策和临床判断是有效管理骨关节炎(OA)患者的关键，尤其是当一系列的OA指南在最佳行动方案上存在分歧时。Read more．

Stable, Supportive Shoes Reduce Walking Pain in Severe Knee OA

根据在2021年OARSI世界大会上提交的一项随机对照试验结果，对于严重膝骨关节炎患者来说，穿稳定、有支持性的鞋子比穿平底、灵活的鞋子更能减轻膝盖疼痛。Learn more．

Products that are easy to use make life less painful for everyone. Find arthritis-friendly products that have earned the Arthritis Foundation Ease of Use seal and take the pain out of everyday chores.Search Ease of Use products．