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Psoriatic Arthritis Research Briefs: Fractures, Depression, RCI

Keep up-to-date on the latest psoriatic arthritis (PsA) research with our brief research summaries.

Fracture Risk Factors Increased in PsA
If you have PsA, it’s important to pay attention to your bones as well as your skin and joints, according to a recent study. The study found increased risk factors for osteoporotic fractures among more than 168,100 people with either PsA or psoriasis compared to people with rheumatoid arthritis and controls. Risk factors included diabetes, smoking, alcohol and oral corticosteroid and antidepressant use. The authors say screening and management of osteoporosis should be considered for patients with psoriasis and PsA.

Source:Annals of the Rheumatic Diseases, May 2017

Depression Linked to Increased PsA Risk
People with psoriasis who also are depressed may be at increased risk for developing PsA, new research shows. Using a primary care database of 73,447 patients followed for 25 years, Canadian researchers found that people with psoriasis who were also diagnosed with a major depressive disorder were up to 37% more likely to develop PsA.

The authors say their study is among the first to offer insight into how depression may be linked to psoriatic arthritis and suggests a need for heightened prevention and management of major depressive disorders in patients with psoriasis.

Source: Journal of Investigative Dermatology, April 2017

RCI May Help Hard-to-Control PsA
最近的一项研究表明,当多重治疗不能控制PsA时,储存库促肾上腺皮质激素注射(RCI)可能是一种安全有效的治疗选择。在一项针对难治性PsA患者的小型研究中,所有9名患者的RCI皮肤和关节疾病至少有短暂改善;但是,有3名患者因副作用不得不停止用药。

Source:Open Access Rheumatology, published online November 2016

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